About Huayu
IVF Facility
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AI Management- The AI management system can integrate a large amount of data, and in the process accomplish deep learning and training. This data is then incorporated into the module calculations to predict the results which can be used in a variety of areas related to reproduction : ●Assessment of male and female fertility ●Prediction of egg quality ●Prediction of sperm quality ●Fertilized eggs and embryo prediction ●Prediction of pregnancy rates ●Genetic and genetic diagnosis prediction
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RI Witness- HuaYu uses an electronic system based on RFID technology (RI Witness) to enable accurate patient identification at each stage of ART procedure, while matching specimens and performing continuous monitoring to reduce the chance of human errors. Other advantages include: enhance process accuracy, efficiency, traceability, and versatile quality control. In addition, RI witness can also promote high volumes of work, data collection and auditing , as well as establish accountability and reducing liability.
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SCA® CASA System- SCA® CASA System for semen analysis allows the accurate, repetitive and automatic assessment of the following sperm parameters: motility, concentration, morphology, DNA fragmentation, vitality, acrosome reaction and leukocytes. According to the WHO laboratory manual for the examination and processing of human semen, the results of the "forward" movement sperm concentration and movement characteristics detected by CASA have significant correlations with in vitro fertilization rates and the time required for conception. Huayu fertility can provide you a comprehensive sperm analysis report. Based on the CASA result, and combined with the years of experience, by using newly developed and verified sperm chip ( A collaboration with JiaTung University), we will harvest the best spermatozoa to fertilize your oocyte via IVF or ICSI.
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Embryoscope Time-Lapse System- We have adapted the most advanced real-time monitoring system for recording and observing cultured embryos without relocating embryos out of the incubator. Those time-lapse images not only can be shared with patients, but also can be used to select high quality embryos based on its developmental dynamics and with expert knowledge.
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Laser Embryo Biopsy- The development of early embryo after fertilization is surrounded by zona pellucida (ZP). The role of ZP during implantation is unclear. However, the matrix of the ZP is altered according to the developing embryo. The changes include enzymes in the uterus dissolving the ZP from the outside and enzymes from the embryo itself digesting the ZP from the inside. Adding the pressure caused by the proliferation of the embryo , those are the mechanisms of the ZP thinning and breaking. Therefore, ZP must be broken and then the embryo hatched before implantation. Sometimes the ZP may be too hard and too thick to be removed by lytic enzymes as well as other obstacles that resulting in failure of the embryo hatching and subsequently implantation. For infertile women older than 38 years old or with repeated IVF failures, assisted hatching will be considered to increase embryo implantation rate in order to increase the chance of IVF success. The assisted hatching of embryos is done by laser to burn away and make ZP thinner, which can help embryos break through the shell of the ZP and allow the hatching of the embryos.
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Micromanipulation- Micromanipulation refers to a method of using a micromanipulator to control the movement of the microinjection needle in the microscope's field under a high-powered inverted microscope to perform cell or early embryo manipulation. Micromanipulation techniques include nuclear transfer, microinjection, making chimera technology, embryo transfer, and microdissection. In artificial reproduction technology, micromanipulation is used for enucleation, spindle transfer, mitochondrial replacement, intracytoplasmic sperm injection and embryo biopsy. The last two are often used in the ART laboratory. Intracytoplasmic sperm injection (ICSI) is an in vitro fertilization technique. This technique uses a pipette to inject sperm into the oocyte's cytoplasm, which need to be both accurate and fast. Our inverted microscope system improves ICSI quality with microscope accuracy and speed. This microscope uses an optical system developed specifically for ICSI, which clearly shows the spindle body of metaphase II oocytes through the eyepiece. By confirming the maturation stage of the oocyte and the electric device of the pipette injection, ICSI can be accelerated, the pressure of the oocyte can be relieved, and help our embryologist to operate in a precise manner. Embryo Biopsy is an important step in pre-implantation genetic diagnosis and screening (PGD / PGS). It must ensure that the cells obtained are suitable for the requirements of genetic diagnosis, and that the operation are suitable and reasonable to reduce impact on expected embryonic development. It is also important to choose the right time and the right method for embryo biopsy
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Aseptic zero pollution- In order to protect you, your eggs, and your embryos, our laboratory design is centered around the embryo lab, which is a cleanroom ISO3 / class1000 with negative air pressure; even the sperm room, and the cryopreservation room are also at ISO4 level. In addition to being dust-free and sterile, Coda air filtration system is added to remove volatile organic compounds in the laboratory. All eggs and embryos are operated in a higher-grade, sterile, no-dust biological safety cabinet with class100. The countertop also has a constant temperature warm plate to protect the egg and embryo. The interconnection between the operating rooms (egg retrieval and implantation room) and the embryo lab is also provided by a sterile biosafety cabinet which provides stable and clean air quality and constant temperature.
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Cryopreservation- Cryopreservation is a method to fill egg sperm and embryos with cryo-fluid into cryotubes, then to slowly or quickly cool down cells, and allow them to be stored in liquid nitrogen at -196 ° C. Our center uses vitrification to freeze eggs and embryos.This technology mainly uses a high concentration and a very small amount of cryoprotectant to freeze and store embryos or eggs in liquid nitrogen in an ultra-fast (about 23000 ° C / minute) cooling environment. The eggs or embryos can be waiting in suspension until necessary and in accordance with the patient's physiological cycle. When do I need to freeze eggs or embryos? 1. The remaining embryos after implantation : When you perform IVF treatment, if the number of embryos obtained exceeds the number of embryos required for the current implantation, the remaining embryos can be frozen and stored for future use. 2. Conditions are not ideal : During your egg retrieval cycle, if embryo implantation is not possible or appropriate, such as severe ovarian hyperstimulation syndrome, hormonal index off, traveling, work, you can have the embryo cryopreserved for future use. 3. Fertility Preservation : Single women can use ART to "freeze the eggs" and save their precious young eggs for future use. In addition, if the disease needs to be treated for possible damage to the ovarian function (for example: radiation therapy, chemotherapy), ART can be used to retrieve eggs before therapy, and freeze the eggs to rescue fertility; The person can choose to fertilize the eggs or zygote for future reproductive opportunities. 4. Donor eggs preservation : If the physiological cycles of the egg donor and the recipient are not easy to match, the embryo / egg can be frozen first, and then the thawing and IVF can be performed when the timing is appropriate. How long can I keep it frozen? Under the proper care of a professional and a stable freezing environment, the freezing can be last for decades or even hundreds of years. However, it must be in accordance with the local "Artificial Reproduction Law". Regulations indicate the embryo can be stored for ten years. You might extend the storage period after filling in a consent form.